The Matthew DeGori Lowe Syndrome Foundation was founded in 2006 by the parents of a child diagnosed with Lowe Syndrome. The Foundation is a non- profit 501(c)3 recognized as a public charity by the Internal Revenue Service. The mission of the Foundation is to raise much needed funds to support medical research associated with Lowe Syndrome (LS).

Lowe Syndrome is a genetic disease which affects the kidneys, eyes, brain, bones, and muscles. Multiple physical and mental handicaps are associated with this disease. Lowe Syndrome is a terminal illness in which there is no known cure and treatment is symptomatic.